To analyze the use of steel­concrete composite structures in single­storey industrial building frames, including those related to transport. To explore potential reductions in material consumption and overall costs associated with the proposed innovative composite building frame design, while enhancing rigidity and reliability. Methods: Analysis of established design solutions for composite structures and calculation of various frame options using calculation software packages in accordance with current methodologies. Results: Conventional industrial building frames that utilize metal structures do not consistently provide adequate rigidity or resistance to progressive collapse. They are susceptible to various forms of damage from force and mechanical stress, as well as specific loads and effects, particularly in transportation context. Typically, frames for industrial buildings with large spans require additional structural measures to mitigate the risk of progressive collapse. The Department of “Building Structures, Buildings, and Constructions” at SPTU (Petersburg State Transport University) is engaged in the development of advanced structural solutions for building frames and their components characterized by enhanced rigidity, load­bearing capacity, and reliability. An innovative design for a highly rigid industrial building has been proposed, which includes columns, roof trusses, gantry beams, as well as a bracing system, roofing, and wall panels. The roofing is constructed from ribbed reinforced concrete slabs with monolithic concrete joints, with the supporting transverse ribs rigidly connected to the upper chord of the roof trusses through welded joints. The wall panels are made of reinforced concrete slabs with monolithic concrete joints, where the supporting transverse ribs are securely welded to the outer surface of the columns. Several options for an industrial building frame have been calculated, establishing the reduction in the weight of the structure, its cost, and the increase in the rigidity of the innovative design. Practical significance: The primary advantages of steel­concrete composite frame structures in single­storey industrial buildings have been evaluated. The innovative frame design demonstrates a weight reduction of 18%, a cost decrease of 25%, and a rigidity increase of 35% compared to traditional metal frame designs. The proposed frame design may prove to be effective in industrial buildings with large spans, as well as on transportation facilities.