Purpose: To identify the occupational risks at St. Petersburg Information and Computing Center (SPb ICC), a structural unit of the Main Computing Center (MCC) and a “Russian Railways” branch. To investigate the issue of enhancing labour management quality through clear structuring and coordination of actions to ensure effective work, as defined by the labour regulations in St. Petersburg ICC, which are conditionally divided into external and internal sources. Methods: A comparative analysis of the indicators characterising the personnel listing; assessment of the results of personnel recruitment, their retraining and upgrading of skills; the maturity of technological processes and labour rationing; the level of labour remuneration, and the compliance of the actual level of labour management with the optimal level in terms of the efficiency of labour resources. This was undertaken in accordance with the Russian labour legislation norms and JSC “Russian Railways” regulations, with the overarching objective being to increase JSC “Russian Railways” economic efficiency. Results: The occupational labour risks associated with the management system at St. Petersburg ICC have been identified. The risks have been categorized as follows: personnel, production and financial. A risk matrix has been developed, the parameters of which are as follows: the probability of their occurrence and the degree of impact on business processes, with a subjective assessment of risks in the context of the research results obtained. A set of recommendations for minimizing risks has been formulated. Practical significance: The results obtained propose and justify a number of measures aimed at optimizing business processes to improve the efficiency of labour management, which will contribute to the sustainable development of the activities of the MCC structural divisions within Russian Railways.